6T3F
Crystal structure Nipah virus fusion glycoprotein in complex with a neutralising Fab fragment
Summary for 6T3F
Entry DOI | 10.2210/pdb6t3f/pdb |
Descriptor | Fusion glycoprotein F0, Fab66 light chain, Fab66 heavy chain, ... (5 entities in total) |
Functional Keywords | fusion protein, glycoprotein, antibody, fab, viral protein |
Biological source | Nipah virus More |
Total number of polymer chains | 3 |
Total formula weight | 103688.02 |
Authors | Avanzato, V.A.,Pryce, R.,Walter, T.S.,Bowden, T.A. (deposition date: 2019-10-10, release date: 2019-11-27, Last modification date: 2024-01-24) |
Primary citation | Avanzato, V.A.,Oguntuyo, K.Y.,Escalera-Zamudio, M.,Gutierrez, B.,Golden, M.,Kosakovsky Pond, S.L.,Pryce, R.,Walter, T.S.,Seow, J.,Doores, K.J.,Pybus, O.G.,Munster, V.J.,Lee, B.,Bowden, T.A. A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex. Proc.Natl.Acad.Sci.USA, 116:25057-25067, 2019 Cited by PubMed: 31767754DOI: 10.1073/pnas.1912503116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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