6T3F

Crystal structure Nipah virus fusion glycoprotein in complex with a neutralising Fab fragment

6T3F の概要

• エントリーDOI: 10.2210/pdb6t3f/pdb
• 分子名称: Fusion glycoprotein F0, Fab66 light chain, Fab66 heavy chain, ... (5 entities in total)
• 機能のキーワード: fusion protein, glycoprotein, antibody, fab, viral protein
• 由来する生物種: Nipah virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 103688.02

構造登録者

Avanzato, V.A.,Pryce, R.,Walter, T.S.,Bowden, T.A. (登録日: 2019-10-10, 公開日: 2019-11-27, 最終更新日: 2024-01-24)

• 主引用文献: Avanzato, V.A.,Oguntuyo, K.Y.,Escalera-Zamudio, M.,Gutierrez, B.,Golden, M.,Kosakovsky Pond, S.L.,Pryce, R.,Walter, T.S.,Seow, J.,Doores, K.J.,Pybus, O.G.,Munster, V.J.,Lee, B.,Bowden, T.A.; A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.; Proc.Natl.Acad.Sci.USA, 116:25057-25067, 2019; PubMed: 31767754; DOI: 10.1073/pnas.1912503116

実験手法

X-RAY DIFFRACTION (3.2 Å)