6T2L
Streptavidin variants harbouring an artificial organocatalyst based cofactor
Summary for 6T2L
Entry DOI | 10.2210/pdb6t2l/pdb |
Descriptor | Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | artificial cofactor, streptavidin, catalyst, biotin-binding protein |
Biological source | Streptomyces avidinii |
Total number of polymer chains | 1 |
Total formula weight | 16996.59 |
Authors | Lechner, H.,Hocker, B. (deposition date: 2019-10-09, release date: 2020-10-14, Last modification date: 2024-01-24) |
Primary citation | Lechner, H.,Emann, V.R.,Breuning, M.,Hocker, B. An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22:1573-1577, 2021 Cited by PubMed: 33400831DOI: 10.1002/cbic.202000880 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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