6T2L

Streptavidin variants harbouring an artificial organocatalyst based cofactor

6T2L の概要

• エントリーDOI: 10.2210/pdb6t2l/pdb
• 分子名称: Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: artificial cofactor, streptavidin, catalyst, biotin-binding protein
• 由来する生物種: Streptomyces avidinii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16996.59

構造登録者

Lechner, H.,Hocker, B. (登録日: 2019-10-09, 公開日: 2020-10-14, 最終更新日: 2024-01-24)

• 主引用文献: Lechner, H.,Emann, V.R.,Breuning, M.,Hocker, B.; An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*.; Chembiochem, 22:1573-1577, 2021; PubMed: 33400831; DOI: 10.1002/cbic.202000880

実験手法

X-RAY DIFFRACTION (1 Å)