6T0M

Cationic Trypsin in Complex with a D-Phe-Pro-diaminopyridine derivative

6T0M の概要

• エントリーDOI: 10.2210/pdb6t0m/pdb
• 分子名称: Cationic trypsin, DIMETHYL SULFOXIDE, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: hydrolase, protease, serine protease, digestion, metal ion binding
• 由来する生物種: Bos taurus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26481.06

構造登録者

Ngo, K.,Heine, A.,Klebe, G. (登録日: 2019-10-03, 公開日: 2020-05-13, 最終更新日: 2024-01-24)

• 主引用文献: Ngo, K.,Collins-Kautz, C.,Gerstenecker, S.,Wagner, B.,Heine, A.,Klebe, G.; Protein-Induced Change in Ligand Protonation during Trypsin and Thrombin Binding: Hint on Differences in Selectivity Determinants of Both Proteins?; J.Med.Chem., 63:3274-3289, 2020; PubMed: 32011145; DOI: 10.1021/acs.jmedchem.9b02061

実験手法

X-RAY DIFFRACTION (1.51 Å)