6SWS
The DBB dimerization domain of B-cell adaptor for PI3K (BCAP) is required for down regulation of inflammatory signalling through the Toll-like receptor pathway
Summary for 6SWS
Entry DOI | 10.2210/pdb6sws/pdb |
Descriptor | Phosphoinositide 3-kinase adapter protein 1 (1 entity in total) |
Functional Keywords | dbb, tig/ipt, transcription factor, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 5 |
Total formula weight | 62370.35 |
Authors | Lauenstein, J.U.,Scherm, M.J.,Udgata, A.,Moncrieffe, M.C.,Fisher, D.,Gay, N.J. (deposition date: 2019-09-23, release date: 2020-02-19, Last modification date: 2024-05-15) |
Primary citation | Lauenstein, J.U.,Scherm, M.J.,Udgata, A.,Moncrieffe, M.C.,Fisher, D.I.,Gay, N.J. Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain. J Immunol., 204:2269-2276, 2020 Cited by PubMed: 32198144DOI: 10.4049/jimmunol.1901210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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