6SWS

The DBB dimerization domain of B-cell adaptor for PI3K (BCAP) is required for down regulation of inflammatory signalling through the Toll-like receptor pathway

6SWS の概要

• エントリーDOI: 10.2210/pdb6sws/pdb
• 分子名称: Phosphoinositide 3-kinase adapter protein 1 (1 entity in total)
• 機能のキーワード: dbb, tig/ipt, transcription factor, transcription
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 62370.35

構造登録者

Lauenstein, J.U.,Scherm, M.J.,Udgata, A.,Moncrieffe, M.C.,Fisher, D.,Gay, N.J. (登録日: 2019-09-23, 公開日: 2020-02-19, 最終更新日: 2024-05-15)

• 主引用文献: Lauenstein, J.U.,Scherm, M.J.,Udgata, A.,Moncrieffe, M.C.,Fisher, D.I.,Gay, N.J.; Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain.; J Immunol., 204:2269-2276, 2020; PubMed: 32198144; DOI: 10.4049/jimmunol.1901210

実験手法

X-RAY DIFFRACTION (3 Å)