6SSB

syk in complex with compound 30

6SSB の概要

• エントリーDOI: 10.2210/pdb6ssb/pdb
• 分子名称: Tyrosine-protein kinase SYK, ~{N}-[4-[5-[(dimethylamino)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-yl]-3-methyl-1-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,5-a]pyridin-7-amine (3 entities in total)
• 機能のキーワード: syk kinase transferase inhibitor, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35325.46

構造登録者

Read, J.A. (登録日: 2019-09-06, 公開日: 2020-09-30, 最終更新日: 2024-05-15)

• 主引用文献: Read, J.A.; Discovery of a Series of Potent, Selective and Orally Bioavailable SYK Inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.08 Å)