6SQE

Crystal structure of CREBBP bromodomain complexed with KD341

Summary for 6SQE

• Entry DOI: 10.2210/pdb6sqe/pdb
• Descriptor: CREB-binding protein, ~{N}-[3-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]-5-(1-methylpyrazol-3-yl)phenyl]-5-[(4-methylpiperazin-1-yl)methyl]furan-2-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, crebbp, bromodomain, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14870.08

Authors

Bedi, R.K.,Kirillova, M.,Nevado, C.,Caflisch, A. (deposition date: 2019-09-03, release date: 2020-09-30, Last modification date: 2024-01-24)

• Primary citation: Bedi, R.K.,Kirillova, M.,Nevado, C.,Caflisch, A.; Crystal structure of CREBBP bromodomain complexed with KD341; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.506 Å)