6SPK

A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6

Summary for 6SPK

Entry DOI	10.2210/pdb6spk/pdb
Descriptor	Superoxide dismutase [Cu-Zn], ZINC ION, 2-selanyl-~{N}-[3-[4-(trifluoromethyl)phenyl]phenyl]benzamide, ... (9 entities in total)
Functional Keywords	a4v sod1 mutant, ebselen, ebselen derivatives, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	101472.54
Authors	Chantadul, V.,Amporndanai, K.,Wright, G.,Shahid, M.,Antonyuk, S.,Hasnain, S. (deposition date: 2019-09-01, release date: 2020-03-18, Last modification date: 2024-01-24)
Primary citation	Chantadul, V.,Wright, G.S.A.,Amporndanai, K.,Shahid, M.,Antonyuk, S.V.,Washbourn, G.,Rogers, M.,Roberts, N.,Pye, M.,O'Neill, P.M.,Hasnain, S.S. Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3:97-97, 2020 Cited by PubMed: 32139772 DOI: 10.1038/s42003-020-0826-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation