6SMP

AntDE:AntF (holo): type II PKS acyl-carrier protein in complex with its ketosynthase bound to the hexaketide

Summary for 6SMP

Entry DOI	10.2210/pdb6smp/pdb
Related	6SM6 6SMO
Descriptor	Acyl carrier protein, PKS_KS domain-containing protein, Ketoacyl_synth_N domain-containing protein, ... (5 entities in total)
Functional Keywords	natural product biosynthesis, polyketides, minimal pks system, anthraquinone, chain elongation, catalysis, protein binding
Biological source	Photorhabdus luminescens More
Total number of polymer chains	12
Total formula weight	398412.98
Authors	Braeuer, A.,Zhou, Q.,Grammbitter, G.L.C.,Schmalhofer, M.,Ruehl, M.,Kaila, V.R.I.,Bode, H.,Groll, M. (deposition date: 2019-08-22, release date: 2020-05-27, Last modification date: 2024-01-24)
Primary citation	Brauer, A.,Zhou, Q.,Grammbitter, G.L.C.,Schmalhofer, M.,Ruhl, M.,Kaila, V.R.I.,Bode, H.B.,Groll, M. Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis. Nat.Chem., 12:755-763, 2020 Cited by PubMed: 32632186 DOI: 10.1038/s41557-020-0491-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation