6SLE

Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+

Summary for 6SLE

• Entry DOI: 10.2210/pdb6sle/pdb
• Descriptor: Oxidoreductase, putative, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: amine, imine, nadph, oxidoreductase
• Biological source: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
• Total number of polymer chains: 8
• Total formula weight: 246230.11

Authors

Sharma, M.,Mangas-Sanchez, J.,Turner, N.J.,Grogan, G. (deposition date: 2019-08-19, release date: 2020-06-24, Last modification date: 2024-01-24)

• Primary citation: Mangas-Sanchez, J.,Sharma, M.,Cosgrove, S.C.,Ramsden, J.I.,Marshall, J.R.,Thorpe, T.W.,Palmer, R.B.,Grogan, G.,Turner, N.J.; Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.; Chem Sci, 11:5052-5057, 2020; PubMed: 34122962; DOI: 10.1039/d0sc02253e

Experimental method

X-RAY DIFFRACTION (2.77 Å)