6SFG

CRYSTAL STRUCTURE OF DHQ1 FROM SALMONELLA TYPHI COVALENTLY MODIFIED BY COMPOUND 9

6SFG の概要

• エントリーDOI: 10.2210/pdb6sfg/pdb
• 分子名称: 3-dehydroquinate dehydratase, (1~{R},3~{S},4~{R},5~{R})-3-methyl-4,5-bis(hydroxyl)cyclohexane-1-carboxylic acid, (1~{S},3~{R},4~{S},5~{R})-3-methyl-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic Acid, ... (4 entities in total)
• 機能のキーワード: lyase activity, chorismate biosynthetic process, 3-dehydroquinase, covalent inhibitor, lyase
• 由来する生物種: Salmonella typhi
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28045.38

構造登録者

Sanz-Gaitero, M.,Lence, E.,Maneiro, M.,Thompson, R.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (登録日: 2019-08-01, 公開日: 2020-04-15, 最終更新日: 2024-01-24)

• 主引用文献: Lence, E.,Maneiro, M.,Sanz-Gaitero, M.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C.; Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product.; Chemistry, 26:8035-8044, 2020; PubMed: 32259333; DOI: 10.1002/chem.202000759

実験手法

X-RAY DIFFRACTION (1.23 Å)