6S9K

Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS

Summary for 6S9K

Entry DOI	10.2210/pdb6s9k/pdb
Descriptor	14-3-3 protein gamma, Caspase-2, 1,1,1,3,3,3-hexafluoropropan-2-ol, ... (4 entities in total)
Functional Keywords	14-3-3, caspase-2, phosphorylation, nls, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	31432.92
Authors	Alblova, M.,Obsil, T.,Obsilova, V. (deposition date: 2019-07-15, release date: 2020-01-22, Last modification date: 2024-01-24)
Primary citation	Kalabova, D.,Filandr, F.,Alblova, M.,Petrvalska, O.,Horvath, M.,Man, P.,Obsil, T.,Obsilova, V. 14-3-3 protein binding blocks the dimerization interface of caspase-2. Febs J., 287:3494-3510, 2020 Cited by PubMed: 31961068 DOI: 10.1111/febs.15215 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation