6S8F
Structure of nucleotide-bound Tel1/ATM
Summary for 6S8F
Entry DOI | 10.2210/pdb6s8f/pdb |
EMDB information | 10120 |
Descriptor | Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total) |
Functional Keywords | kinase, dna damage response, cryoem, phosphatidylinositol-3-kinase-like kinase, hydrolase |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 586219.81 |
Authors | Yates, L.A.,Williams, R.M.,Ayala, R.,Zhang, X. (deposition date: 2019-07-09, release date: 2019-10-30, Last modification date: 2024-05-22) |
Primary citation | Yates, L.A.,Williams, R.M.,Hailemariam, S.,Ayala, R.,Burgers, P.,Zhang, X. Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28:96-104.e3, 2020 Cited by PubMed: 31740029DOI: 10.1016/j.str.2019.10.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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