6S8F

Structure of nucleotide-bound Tel1/ATM

6S8F の概要

• エントリーDOI: 10.2210/pdb6s8f/pdb
• EMDBエントリー: 10120
• 分子名称: Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: kinase, dna damage response, cryoem, phosphatidylinositol-3-kinase-like kinase, hydrolase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 586219.81

構造登録者

Yates, L.A.,Williams, R.M.,Ayala, R.,Zhang, X. (登録日: 2019-07-09, 公開日: 2019-10-30, 最終更新日: 2024-05-22)

• 主引用文献: Yates, L.A.,Williams, R.M.,Hailemariam, S.,Ayala, R.,Burgers, P.,Zhang, X.; Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.; Structure, 28:96-104.e3, 2020; PubMed: 31740029; DOI: 10.1016/j.str.2019.10.012

実験手法

ELECTRON MICROSCOPY (4 Å)