6S1U
Crystal structure of dimeric M-PMV protease C7A/D26N/C106A mutant in complex with inhibitor
Summary for 6S1U
Entry DOI | 10.2210/pdb6s1u/pdb |
Related | 1az5 1bai 1ivp 2fmb 2rsp 3hvp 3liy 3slz 3sqf 4fiv 4hvp |
Descriptor | Gag-Pro-Pol polyprotein, PRO-0A1-VAL-PSA-ALA-MET-THR (3 entities in total) |
Functional Keywords | mason-pfizer monkey virus, m-pmv, retrovirus, retropepsin, aspartic protease, dimerization, inhibitor, flap structure, hydrolase |
Biological source | Mason-Pfizer monkey virus (MPMV) More |
Total number of polymer chains | 3 |
Total formula weight | 26685.73 |
Authors | Wosicki, S.,Gilski, M.,Jaskolski, M.,Zabranska, H.,Pichova, I. (deposition date: 2019-06-19, release date: 2019-10-16, Last modification date: 2024-01-24) |
Primary citation | Wosicki, S.,Gilski, M.,Zabranska, H.,Pichova, I.,Jaskolski, M. Comparison of a retroviral protease in monomeric and dimeric states. Acta Crystallogr D Struct Biol, 75:904-917, 2019 Cited by PubMed: 31588922DOI: 10.1107/S2059798319011355 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report