6S07

Structure of formylglycine-generating enzyme at 1.04 A in complex with copper and substrate reveals an acidic pocket for binding and acti-vation of molecular oxygen.

6S07 の概要

• エントリーDOI: 10.2210/pdb6s07/pdb
• 分子名称: Formylglycine-generating enzyme, Abz-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY-ARG, COPPER (I) ION, ... (6 entities in total)
• 機能のキーワード: formylglycine-generating enzyme, complex, substrate analog, copper, transferase
• 由来する生物種: Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NBRC 15933 / NCIMB 10081 / Henssen B9); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35166.88

構造登録者

Leisinger, F.,Miarzlou, D.A.,Seebeck, F.P. (登録日: 2019-06-14, 公開日: 2019-06-26, 最終更新日: 2024-01-24)

• 主引用文献: Miarzlou, D.A.,Leisinger, F.,Joss, D.,Haussinger, D.,Seebeck, F.P.; Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen.; Chem Sci, 10:7049-7058, 2019; PubMed: 31588272; DOI: 10.1039/c9sc01723b

実験手法

X-RAY DIFFRACTION (1.04 Å)