6RZ4
Crystal structure of cysteinyl leukotriene receptor 1 in complex with pranlukast
6RZ4 の概要
エントリーDOI | 10.2210/pdb6rz4/pdb |
分子名称 | Cysteinyl leukotriene receptor 1,Soluble cytochrome b562,Cysteinyl leukotriene receptor 1, pranlukast, SODIUM ION, ... (6 entities in total) |
機能のキーワード | gpcr, lcp, membrane protein, cysteinyl leukotriene, ltd4, cyslt1, cysltr1, cyslt1r asthma, pranlukast, bril, sodium site, cysteinyl leukotriene receptor 1 |
由来する生物種 | Homo sapiens (Human) 詳細 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 51922.90 |
構造登録者 | Luginina, A.,Gusach, A.,Marin, E.,Mishin, A.,Brouillette, R.,Popov, P.,Shiryaeva, A.,Besserer-Offroy, E.,Longpre, J.M.,Lyapina, E.,Ishchenko, A.,Patel, N.,Polovinkin, V.,Safronova, N.,Bogorodskiy, A.,Edelweiss, E.,Liu, W.,Batyuk, A.,Gordeliy, V.,Han, G.W.,Sarret, P.,Katritch, V.,Borshchevskiy, V.,Cherezov, V. (登録日: 2019-06-12, 公開日: 2019-10-30, 最終更新日: 2024-01-24) |
主引用文献 | Luginina, A.,Gusach, A.,Marin, E.,Mishin, A.,Brouillette, R.,Popov, P.,Shiriaeva, A.,Besserer-Offroy, E.,Longpre, J.M.,Lyapina, E.,Ishchenko, A.,Patel, N.,Polovinkin, V.,Safronova, N.,Bogorodskiy, A.,Edelweiss, E.,Hu, H.,Weierstall, U.,Liu, W.,Batyuk, A.,Gordeliy, V.,Han, G.W.,Sarret, P.,Katritch, V.,Borshchevskiy, V.,Cherezov, V. Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Sci Adv, 5:eaax2518-eaax2518, 2019 Cited by PubMed: 31633023DOI: 10.1126/sciadv.aax2518 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.7 Å) |
構造検証レポート
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