6RUL

Crystal structure of GFP-LAMA-F98 - a GFP enhancer nanobody with cpDHFR insertion and TMP and NADPH

Summary for 6RUL

Entry DOI	10.2210/pdb6rul/pdb
Related	6RUM
Descriptor	GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion, TRIMETHOPRIM, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	lama, nanobody, circular permutant of dhfr, tmp, nadph, protein binding
Biological source	Lama glama More
Total number of polymer chains	1
Total formula weight	32170.56
Authors	Farrants, H.,Tarnawski, M.,Mueller, T.G.,Otsuka, S.,Hiblot, J.,Koch, B.,Kueblbeck, M.,Kraeusslich, H.-G.,Ellenberg, J.,Johnsson, K. (deposition date: 2019-05-28, release date: 2020-02-12, Last modification date: 2024-01-24)
Primary citation	Farrants, H.,Tarnawski, M.,Muller, T.G.,Otsuka, S.,Hiblot, J.,Koch, B.,Kueblbeck, M.,Krausslich, H.G.,Ellenberg, J.,Johnsson, K. Chemogenetic Control of Nanobodies. Nat.Methods, 17:279-282, 2020 Cited by PubMed: 32066961 DOI: 10.1038/s41592-020-0746-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation