6RQK

Crystal structure of GH125 1,6-alpha-mannosidase from Clostridium perfringens in complex with mannoimidazole

6RQK の概要

• エントリーDOI: 10.2210/pdb6rqk/pdb
• 分子名称: Alpha-1,6-mannosidase, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL (3 entities in total)
• 機能のキーワード: carbohydrate, inhibitor, glycoside hydrolase, complex, hydrolase
• 由来する生物種: Clostridium perfringens str. 13
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102524.75

構造登録者

Males, A.,Davies, G.J. (登録日: 2019-05-16, 公開日: 2019-08-28, 最終更新日: 2024-01-24)

• 主引用文献: Males, A.,Speciale, G.,Williams, S.J.,Davies, G.J.; Distortion of mannoimidazole supports a B2,5boat transition state for the family GH125 alpha-1,6-mannosidase from Clostridium perfringens.; Org.Biomol.Chem., 17:7863-7869, 2019; PubMed: 31407758; DOI: 10.1039/c9ob01161g

実験手法

X-RAY DIFFRACTION (1.85 Å)