6RPB
Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV
Summary for 6RPB
Entry DOI | 10.2210/pdb6rpb/pdb |
Related | 6RP9 6RPA |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Heteroclitic NY-ESO-1 157-165 peptide, ... (6 entities in total) |
Functional Keywords | t-cell receptor, peptide-human leukocyte antigen complex, ny-eso-1, cancer testis antigen, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 20 |
Total formula weight | 381187.40 |
Authors | Coles, C.H.,Mulvaney, R.,Malla, S.,Lloyd, A.,Smith, K.,Chester, F.,Knox, A.,Stacey, A.R.,Dukes, J.,Baston, E.,Griffin, S.,Vuidepot, A.,Jakobsen, B.K.,Harper, S. (deposition date: 2019-05-14, release date: 2020-01-15, Last modification date: 2024-01-24) |
Primary citation | Coles, C.H.,Mulvaney, R.M.,Malla, S.,Walker, A.,Smith, K.J.,Lloyd, A.,Lowe, K.L.,McCully, M.L.,Martinez Hague, R.,Aleksic, M.,Harper, J.,Paston, S.J.,Donnellan, Z.,Chester, F.,Wiederhold, K.,Robinson, R.A.,Knox, A.,Stacey, A.R.,Dukes, J.,Baston, E.,Griffin, S.,Jakobsen, B.K.,Vuidepot, A.,Harper, S. TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204:1943-1953, 2020 Cited by PubMed: 32102902DOI: 10.4049/jimmunol.1900915 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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