6ROH

Cryo-EM structure of the autoinhibited Drs2p-Cdc50p

Summary for 6ROH

• Entry DOI: 10.2210/pdb6roh/pdb
• EMDB information: 4972
• Descriptor: Probable phospholipid-transporting ATPase DRS2, Cell division control protein 50, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: lipid flippase, lipid transport, p-type atpase, ps transport.
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 212976.60

Authors

Timcenko, M.,Lyons, J.A.,Januliene, D.,Ulstrup, J.J.,Dieudonne, T.,Montigny, C.,Ash, M.R.,Karlsen, J.L.,Boesen, T.,Kuhlbrandt, W.,Lenoir, G.,Moeller, A.,Nissen, P. (deposition date: 2019-05-13, release date: 2019-07-03, Last modification date: 2020-07-29)

• Primary citation: Timcenko, M.,Lyons, J.A.,Januliene, D.,Ulstrup, J.J.,Dieudonne, T.,Montigny, C.,Ash, M.R.,Karlsen, J.L.,Boesen, T.,Kuhlbrandt, W.,Lenoir, G.,Moeller, A.,Nissen, P.; Structure and autoregulation of a P4-ATPase lipid flippase.; Nature, 571:366-370, 2019; PubMed: 31243363; DOI: 10.1038/s41586-019-1344-7

Experimental method

ELECTRON MICROSCOPY (2.8 Å)