6RLO

Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop

6RLO の概要

• エントリーDOI: 10.2210/pdb6rlo/pdb
• 分子名称: AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... (7 entities in total)
• 機能のキーワード: antibody, fab, cd9-binding, affinity-improvement, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 233990.53

構造登録者

Neviani, V.,Pearce, N.M.,Pos, W.,Schotte, R.,Spits, H.,Gros, P. (登録日: 2019-05-02, 公開日: 2021-05-12, 最終更新日: 2024-01-24)

• 主引用文献: Neviani, V.,Pos, W.,Schotte, R.,Wagner, K.,Go, D.M.,Fatmawati, C.,Kedde, M.,Claassen, Y.B.,Kroon-Batenburg, L.,Lutz, M.,Verdegaal, E.M.E.,van der Burg, S.H.,Spits, H.,Gros, P.; Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)