6RLM
Crystal structure of AT1412dm Fab fragment
Summary for 6RLM
Entry DOI | 10.2210/pdb6rlm/pdb |
Descriptor | AT1412dm Fab (Heavy Chain), AT1412dm Fab (Light Chain), CHLORIDE ION (3 entities in total) |
Functional Keywords | antibody, fab, cd9-binding, affinity-improvement, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 16 |
Total formula weight | 388501.53 |
Authors | Neviani, V.,Pearce, N.M.,Pos, W.,Schotte, R.,Spits, H.,Gros, P. (deposition date: 2019-05-02, release date: 2021-05-12, Last modification date: 2024-01-24) |
Primary citation | Neviani, V.,Pos, W.,Schotte, R.,Wagner, K.,Go, D.M.,Fatmawati, C.,Kedde, M.,Claassen, Y.B.,Kroon-Batenburg, L.,Lutz, M.,Verdegaal, E.M.E.,van der Burg, S.H.,Spits, H.,Gros, P. Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report