6RLG

Crystal structure of LdtMt2 from Mycobacterium tuberculosis

Summary for 6RLG

Entry DOI	10.2210/pdb6rlg/pdb
Descriptor	L,D-transpeptidase 2, NITRATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
Functional Keywords	beta lactmase, antibiotic resistance, tuberculosis, antimicrobial protein
Biological source	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Total number of polymer chains	2
Total formula weight	77245.58
Authors	Brem, J.,Lohans, C.,Schofield, C. (deposition date: 2019-05-02, release date: 2019-08-14, Last modification date: 2024-01-24)
Primary citation	de Munnik, M.,Lohans, C.T.,Lang, P.A.,Langley, G.W.,Malla, T.R.,Tumber, A.,Schofield, C.J.,Brem, J. Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2with cysteine-reactive inhibitors including ebselen. Chem.Commun.(Camb.), 55:10214-10217, 2019 Cited by PubMed: 31380528 DOI: 10.1039/c9cc04145a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.51000183032 Å)

Structure validation