Crystal structure of Eis2 form Mycobacterium abscessus

Summary for 6RFY

DescriptorEis2, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
Functional Keywordsgcn5 n-acetyltransferase, eis, antibiotic
Biological sourceMycobacteroides abscessus
Total number of polymer chains6
Total molecular weight272352.38
Blaise, M.,Kremer, L.,Olieric, V.,Alsarraf, H.,Ung, K.L. (deposition date: 2019-04-16, release date: 2019-07-10)
Primary citation
Ung, K.L.,Alsarraf, H.M.A.B.,Olieric, V.,Kremer, L.,Blaise, M.
Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
Febs J., 2019
PubMed: 31254444 (PDB entries with the same primary citation)
DOI: 10.1111/febs.14975
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23020 0.9% 0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution