6RCV

PfRH5 bound to monoclonal antibodies R5.011 and R5.016

6RCV の概要

• エントリーDOI: 10.2210/pdb6rcv/pdb
• 関連するPDBエントリー: 6RCO 6RCQ 6RCS 6RCU
• 分子名称: Reticulocyte binding protein homologue 5, R5.011 light chain, R5.011 heavy chain, ... (5 entities in total)
• 機能のキーワード: plasmodium falciparum erythrocyte invasion potentiating antibody neutralising antibody human monoclonal antibody, cell adhesion
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 367202.57

構造登録者

Alanine, D.W.G.,Draper, S.J.,Higgins, M.K. (登録日: 2019-04-11, 公開日: 2019-06-26, 最終更新日: 2019-07-10)

• 主引用文献: Alanine, D.G.W.,Quinkert, D.,Kumarasingha, R.,Mehmood, S.,Donnellan, F.R.,Minkah, N.K.,Dadonaite, B.,Diouf, A.,Galaway, F.,Silk, S.E.,Jamwal, A.,Marshall, J.M.,Miura, K.,Foquet, L.,Elias, S.C.,Labbe, G.M.,Douglas, A.D.,Jin, J.,Payne, R.O.,Illingworth, J.J.,Pattinson, D.J.,Pulido, D.,Williams, B.G.,de Jongh, W.A.,Wright, G.J.,Kappe, S.H.I.,Robinson, C.V.,Long, C.A.,Crabb, B.S.,Gilson, P.R.,Higgins, M.K.,Draper, S.J.; Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.; Cell, 178:216-228.e21, 2019; PubMed: 31204103; DOI: 10.1016/j.cell.2019.05.025

実験手法

X-RAY DIFFRACTION (3.582 Å)