6RB3

Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC variant in complex with its substrate

6RB3 の概要

• エントリーDOI: 10.2210/pdb6rb3/pdb
• 分子名称: Putative dioxygenase (1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase), 2-heptylquinoline-3,4-diol (3 entities in total)
• 機能のキーワード: dioxygenase; alpha/beta hydrolase fold, catalytic triad, quorum sensing, pseudomonas quinolone signal, pseudomonas aeruginosa, hydrolase
• 由来する生物種: Mycobacterium abscessus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 90017.93

構造登録者

Wullich, S.,Kobus, S.,Smits, S.H.,Fetzner, S. (登録日: 2019-04-09, 公開日: 2019-07-03, 最終更新日: 2024-01-24)

• 主引用文献: Wullich, S.C.,Kobus, S.,Wienhold, M.,Hennecke, U.,Smits, S.H.J.,Fetzner, S.; Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC, a mycobacterial dioxygenase of the alpha / beta-hydrolase fold family.; J.Struct.Biol., 207:287-294, 2019; PubMed: 31228546; DOI: 10.1016/j.jsb.2019.06.006

実験手法

X-RAY DIFFRACTION (2.3 Å)