6RAA

CLK1 Kinase domain with bound imidazopyridin inhibitor TP003

Summary for 6RAA

• Entry DOI: 10.2210/pdb6raa/pdb
• Descriptor: Dual specificity protein kinase CLK1, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: inhibitor, kinase, transferase, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 40126.16

Authors

Schroeder, M.,Arrowsmith, C.,Knapp, S.,Bountra, C.,Edwards, A.,Structural Genomics Consortium (SGC) (deposition date: 2019-04-05, release date: 2019-04-24, Last modification date: 2024-01-24)

• Primary citation: Schroeder, M.,Arrowsmith, C.,Knapp, S.,Bountra, C.,Edwards, A.; CLK1 Kinase domain with bound imidazopyridin inhibitor TP003; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)