6RAA

CLK1 Kinase domain with bound imidazopyridin inhibitor TP003

6RAA の概要

• エントリーDOI: 10.2210/pdb6raa/pdb
• 分子名称: Dual specificity protein kinase CLK1, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: inhibitor, kinase, transferase, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40126.16

構造登録者

Schroeder, M.,Arrowsmith, C.,Knapp, S.,Bountra, C.,Edwards, A.,Structural Genomics Consortium (SGC) (登録日: 2019-04-05, 公開日: 2019-04-24, 最終更新日: 2024-01-24)

• 主引用文献: Schroeder, M.,Arrowsmith, C.,Knapp, S.,Bountra, C.,Edwards, A.; CLK1 Kinase domain with bound imidazopyridin inhibitor TP003; To Be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)