6R6W

Structure of recombinant human butyrylcholinesterase in complex with a fluorescent NBD-based probe

6R6W の概要

• エントリーDOI: 10.2210/pdb6r6w/pdb
• 分子名称: Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: butyrylcholinesterase, protein-ligand complex, fluorescent probe, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62849.64

構造登録者

Brazzolotto, X.,Nachon, F.,Knez, D.,Gobec, S. (登録日: 2019-03-28, 公開日: 2020-01-15, 最終更新日: 2024-01-24)

• 主引用文献: Pajk, S.,Knez, D.,Kosak, U.,Zorovic, M.,Brazzolotto, X.,Coquelle, N.,Nachon, F.,Colletier, J.P.,Zivin, M.,Stojan, J.,Gobec, S.; Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes.; J Enzyme Inhib Med Chem, 35:498-505, 2020; PubMed: 31914836; DOI: 10.1080/14756366.2019.1710502

実験手法

X-RAY DIFFRACTION (2.474 Å)