6R65

Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)

6R65 の概要

• エントリーDOI: 10.2210/pdb6r65/pdb
• 関連するPDBエントリー: 5OC9
• 分子名称: Anoctamin-10, CALCIUM ION (2 entities in total)
• 機能のキーワード: membrane protein, calcium activation, transport protein, lipid transport, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 154792.50

構造登録者

Bushell, S.R.,Pike, A.C.W.,Chu, A.,Tessitore, A.,Rotty, B.,Mukhopadhyay, S.,Kupinska, K.,Shrestha, L.,Borkowska, O.,Chalk, R.,Burgess-Brown, N.A.,Love, J.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (登録日: 2019-03-26, 公開日: 2019-05-01, 最終更新日: 2024-01-24)

• 主引用文献: Bushell, S.R.,Pike, A.C.W.,Falzone, M.E.,Rorsman, N.J.G.,Ta, C.M.,Corey, R.A.,Newport, T.D.,Christianson, J.C.,Scofano, L.F.,Shintre, C.A.,Tessitore, A.,Chu, A.,Wang, Q.,Shrestha, L.,Mukhopadhyay, S.M.M.,Love, J.D.,Burgess-Brown, N.A.,Sitsapesan, R.,Stansfeld, P.J.,Huiskonen, J.T.,Tammaro, P.,Accardi, A.,Carpenter, E.P.; The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.; Nat Commun, 10:3956-3956, 2019; PubMed: 31477691; DOI: 10.1038/s41467-019-11753-1

実験手法

X-RAY DIFFRACTION (3.5 Å)