6R3E

Human DNMT3B PWWP domain in complex with triisopropanolamine

Summary for 6R3E

• Entry DOI: 10.2210/pdb6r3e/pdb
• Descriptor: DNA (cytosine-5)-methyltransferase 3B,DNA (cytosine-5)-methyltransferase 3B, Triisopropanolamine, SULFATE ION, ... (4 entities in total)
• Functional Keywords: dnmt3b pwwp domain, histone binding, beta barrel, ligand, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 62334.31

Authors

Rondelet, G.,Dal Maso, T.,Wouters, J. (deposition date: 2019-03-20, release date: 2020-04-08, Last modification date: 2024-01-24)

• Primary citation: Rondelet, G.,Dal Maso, T.,Maniquet, A.,Themans, Q.,Wouters, J.; Targeting PWWP domain of DNMT3B for epigenetic cancer therapy: identification and structural characterization of potential protein-protein interaction inhibitors; To be published,

Experimental method

X-RAY DIFFRACTION (2.269 Å)