6QZV
DPP9 bound to a dipeptide (MP) from the N-terminus of BRCA2
Summary for 6QZV
Entry DOI | 10.2210/pdb6qzv/pdb |
Descriptor | Dipeptidyl peptidase 9, MET-PRO (3 entities in total) |
Functional Keywords | dpp8, dpp9, brca2, dipeptide, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 411493.93 |
Authors | Ross, B.,Geiss-Friedlander, R.,Huber, R. (deposition date: 2019-03-12, release date: 2020-09-30, Last modification date: 2024-01-24) |
Primary citation | Silva-Garcia, M.,Bolgi, O.,Ross, B.,Pilla, E.,Kari, V.,Killisch, M.,Stark, N.,Lenz, C.,Spitzner, M.,Gorrell, M.D.,Grade, M.,Urlaub, H.,Dobbelstein, M.,Huber, R.,Geiss-Friedlander, R. Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair Biorxiv, 2020 Cited by DOI: 10.1101/2020.08.24.265033PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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