Human PIM1 bound to OX0999

Summary for 6QXK

DescriptorSerine/threonine-protein kinase pim-1, Pimtide, 2-[(1-methylpiperidin-4-yl)methylamino]-5-[[2-[4-(trifluoromethyloxy)phenyl]-1,3-thiazol-4-yl]methyl]-1,3-thiazol-4-one, ... (4 entities in total)
Functional Keywordskinase, structural genomics consortium, sgc, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight37667.91
Alexander, L.T.,Elkins, J.M.,Russell, A.,Bountra, C.,Edwards, A.M.,Knapp, S. (deposition date: 2019-03-07, release date: 2019-04-24)
Primary citation
Knapp, S.,Elkins, J.M.,Alexander, L.T.,Russell, A.
PIM1 bound to OX0999
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20610 0.4% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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