6QXK

Human PIM1 bound to OX0999

Summary for 6QXK

DescriptorSerine/threonine-protein kinase pim-1, Pimtide, 2-[(1-methylpiperidin-4-yl)methylamino]-5-[[2-[4-(trifluoromethyloxy)phenyl]-1,3-thiazol-4-yl]methyl]-1,3-thiazol-4-one, ... (4 entities in total)
Functional Keywordskinase, structural genomics consortium, sgc, transferase
Biological sourceHomo sapiens (Human)
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Total number of polymer chains2
Total molecular weight37667.91
Authors
Alexander, L.T.,Elkins, J.M.,Russell, A.,Bountra, C.,Edwards, A.M.,Knapp, S. (deposition date: 2019-03-07, release date: 2019-04-24)
Primary citation
Knapp, S.,Elkins, J.M.,Alexander, L.T.,Russell, A.
PIM1 bound to OX0999
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20610 0.4% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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