6QXA
Structure of membrane bound pyrophosphatase from Thermotoga maritima in complex with imidodiphosphate and N-[(2-amino-6-benzothiazolyl)methyl]-1H-indole-2-carboxamide (ATC)
Summary for 6QXA
| Entry DOI | 10.2210/pdb6qxa/pdb |
| Descriptor | K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, IMIDODIPHOSPHORIC ACID, ... (8 entities in total) |
| Functional Keywords | membrane-bound pyrophosphatase, inhibitor, membrane protein |
| Biological source | Thermotoga maritima MSB8 |
| Total number of polymer chains | 4 |
| Total formula weight | 315374.32 |
| Authors | Vidilaseris, K.,Goldman, A. (deposition date: 2019-03-07, release date: 2019-04-10, Last modification date: 2024-02-07) |
| Primary citation | Vidilaseris, K.,Kiriazis, A.,Turku, A.,Khattab, A.,Johansson, N.G.,Leino, T.O.,Kiuru, P.S.,Boije Af Gennas, G.,Meri, S.,Yli-Kauhaluoma, J.,Xhaard, H.,Goldman, A. Asymmetry in catalysis byThermotoga maritimamembrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor. Sci Adv, 5:eaav7574-eaav7574, 2019 Cited by PubMed: 31131322DOI: 10.1126/sciadv.aav7574 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.41 Å) |
Structure validation
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