6QUT
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Summary for 6QUT
| Entry DOI | 10.2210/pdb6qut/pdb |
| Descriptor | Carbonic anhydrase 9, ZINC ION, 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide, ... (4 entities in total) |
| Functional Keywords | lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 112867.34 |
| Authors | Leitans, J.,Tars, K. (deposition date: 2019-02-28, release date: 2020-03-25, Last modification date: 2024-01-24) |
| Primary citation | Zaksauskas, A.,Capkauskaite, E.,Jezepcikas, L.,Linkuviene, V.,Paketuryte, V.,Smirnov, A.,Leitans, J.,Kazaks, A.,Dvinskis, E.,Manakova, E.,Grazulis, S.,Tars, K.,Matulis, D. Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur.J.Med.Chem., 185:111825-111825, 2020 Cited by PubMed: 31740053DOI: 10.1016/j.ejmech.2019.111825 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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