6QU2
Crystal structure of DYRK1A complexed with FC162 inhibitor
Summary for 6QU2
Entry DOI | 10.2210/pdb6qu2/pdb |
Descriptor | Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | dyrk1a, splicing kinase, kinase inhibitor, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 171994.15 |
Authors | Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-02-26, release date: 2020-03-18, Last modification date: 2024-01-24) |
Primary citation | Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of DYRK1A complexed with FC162 inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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