6QU2

Crystal structure of DYRK1A complexed with FC162 inhibitor

6QU2 の概要

• エントリーDOI: 10.2210/pdb6qu2/pdb
• 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• 機能のキーワード: dyrk1a, splicing kinase, kinase inhibitor, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 171994.15

構造登録者

Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2019-02-26, 公開日: 2020-03-18, 最終更新日: 2024-01-24)

• 主引用文献: Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Besson, T.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of DYRK1A complexed with FC162 inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.9 Å)