6QMS
NF-YB/C Heterodimer in Complex with NF-YA-derived Peptide Stabilized with C11-Hydrocarbon Linker
Summary for 6QMS
Entry DOI | 10.2210/pdb6qms/pdb |
Descriptor | Nuclear transcription factor Y subunit alpha, Nuclear transcription factor Y subunit beta, Nuclear transcription factor Y subunit gamma, ... (4 entities in total) |
Functional Keywords | stapled peptide histone fold transcription factor, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 24570.77 |
Authors | Kiehstaller, S.,Jeganathan, S.,Pearce, N.M.,Wendt, M.,Grossmann, T.N.,Hennig, S. (deposition date: 2019-02-08, release date: 2019-10-02, Last modification date: 2024-01-24) |
Primary citation | Jeganathan, S.,Wendt, M.,Kiehstaller, S.,Brancaccio, D.,Kuepper, A.,Pospiech, N.,Carotenuto, A.,Novellino, E.,Hennig, S.,Grossmann, T.N. Constrained Peptides with Fine-Tuned Flexibility Inhibit NF-Y Transcription Factor Assembly. Angew.Chem.Int.Ed.Engl., 58:17351-17358, 2019 Cited by PubMed: 31539186DOI: 10.1002/anie.201907901 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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