6QM9

Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (open state)

Summary for 6QM9

• Entry DOI: 10.2210/pdb6qm9/pdb
• EMDB information: 4592
• Descriptor: Predicted protein, CALCIUM ION (2 entities in total)
• Functional Keywords: membrane protein, lipid scrambles, tmem16
• Biological source: Nectria haematococca
• Total number of polymer chains: 2
• Total formula weight: 166560.33

Authors

Kalienkova, V.,Clerico Mosina, V.,Bryner, L.,Oostergetel, G.T.,Dutzler, R.,Paulino, C. (deposition date: 2019-02-01, release date: 2019-03-06, Last modification date: 2019-12-18)

• Primary citation: Kalienkova, V.,Clerico Mosina, V.,Bryner, L.,Oostergetel, G.T.,Dutzler, R.,Paulino, C.; Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM.; Elife, 8:-, 2019; PubMed: 30785398; DOI: 10.7554/eLife.44364

Experimental method

ELECTRON MICROSCOPY (3.6 Å)