6QLZ
IDOL F3ab subdomain
Summary for 6QLZ
Entry DOI | 10.2210/pdb6qlz/pdb |
Related | 6QLY |
Descriptor | E3 ubiquitin-protein ligase MYLIP (2 entities in total) |
Functional Keywords | e3 ligase cholesterol metabolism ldlr degradation, ligase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 33388.83 |
Authors | Martinelli, L.,Johansson, P.,Wan, P.T.,Gunnarsson, J.,Guo, H.,Boyd, H. (deposition date: 2019-02-01, release date: 2020-02-19, Last modification date: 2024-01-24) |
Primary citation | Martinelli, L.,Adamopoulos, A.,Johansson, P.,Wan, P.T.,Gunnarsson, J.,Guo, H.,Boyd, H.,Zelcer, N.,Sixma, T.K. Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. J.Biol.Chem., 295:13570-13583, 2020 Cited by PubMed: 32727844DOI: 10.1074/jbc.RA120.014349 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.343 Å) |
Structure validation
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