6QLN
Galectin-3C in complex with fluoroaryl triazole monothiogalactoside derivative 2
Summary for 6QLN
Entry DOI | 10.2210/pdb6qln/pdb |
Descriptor | Galectin-3, (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol (3 entities in total) |
Functional Keywords | lectin, carbohydrate-binding protein, galactose-specific lectin 3, galactoside-binding protein, galbp, ige-6 binding protein, l-31, laminin-binding protein, lectin l-29, mac-2, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16132.53 |
Authors | Kumar, R.,Peterson, K.,Nilsson, U.J.,Logan, D.T. (deposition date: 2019-02-01, release date: 2019-07-10, Last modification date: 2024-01-24) |
Primary citation | Kumar, R.,Ignjatovic, M.M.,Peterson, K.,Olsson, M.,Leffler, H.,Ryde, U.,Nilsson, U.J.,Logan, D.T. Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions. Chemmedchem, 14:1528-1536, 2019 Cited by PubMed: 31246331DOI: 10.1002/cmdc.201900293 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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