6QHD
Lysine acetylated and tyrosine phosphorylated STAT3 in a complex with DNA
Summary for 6QHD
Entry DOI | 10.2210/pdb6qhd/pdb |
Descriptor | Signal transducer and activator of transcription 3, DNA (5'-D(*AP*AP*GP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*TP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*CP*T)-3'), ... (4 entities in total) |
Functional Keywords | lysine acetylation, dna binding, post translational modification, non canonical amino acid, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 147542.48 |
Authors | Arbely, E.,Belo, Y.,Shahar, A.,Zarivach, R. (deposition date: 2019-01-16, release date: 2019-06-19, Last modification date: 2024-01-24) |
Primary citation | Belo, Y.,Mielko, Z.,Nudelman, H.,Afek, A.,Ben-David, O.,Shahar, A.,Zarivach, R.,Gordan, R.,Arbely, E. Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine. Biochim Biophys Acta Gen Subj, 1863:1343-1350, 2019 Cited by PubMed: 31170499DOI: 10.1016/j.bbagen.2019.05.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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