6QFY

CRYSTAL STRUCTURE OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS SPIKE PROTEIN LECTIN DOMAIN

6QFY の概要

• エントリーDOI: 10.2210/pdb6qfy/pdb
• 分子名称: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: sialic acid binding, beta-sandwich, viral spike protein, spike-ntd, viral protein
• 由来する生物種: Porcine hemagglutinating encephalomyelitis virus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68107.54

構造登録者

Huizinga, E.G.,Bakkers, M.,Lang, Y. (登録日: 2019-01-10, 公開日: 2019-02-06, 最終更新日: 2024-01-24)

• 主引用文献: Hulswit, R.J.G.,Lang, Y.,Bakkers, M.J.G.,Li, W.,Li, Z.,Schouten, A.,Ophorst, B.,van Kuppeveld, F.J.M.,Boons, G.J.,Bosch, B.J.,Huizinga, E.G.,de Groot, R.J.; Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.; Proc. Natl. Acad. Sci. U.S.A., 116:2681-2690, 2019; PubMed: 30679277; DOI: 10.1073/pnas.1809667116

実験手法

X-RAY DIFFRACTION (2.97 Å)