6QA2

R80A MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS

Summary for 6QA2

DescriptorNucleoside diphosphate kinase, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, ... (4 entities in total)
Functional Keywordsremodeling, open and closed binding site, transferase
Biological sourceMycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Total number of polymer chains6
Total molecular weight88097.3
Authors
Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F. (deposition date: 2018-12-18, release date: 2019-02-27, Last modification date: 2019-03-20)
Primary citation
Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F.
Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange.
Biochemistry, 58:1440-1449, 2019
PubMed: 30785730 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.8b01308
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21410 0.7% 4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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