6QA2

R80A MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS

6QA2 の概要

• エントリーDOI: 10.2210/pdb6qa2/pdb
• 分子名称: Nucleoside diphosphate kinase, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, ... (4 entities in total)
• 機能のキーワード: remodeling, open and closed binding site, transferase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 88097.30

構造登録者

Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F. (登録日: 2018-12-18, 公開日: 2019-02-27, 最終更新日: 2024-01-24)

• 主引用文献: Dautant, A.,Henri, J.,Wales, T.E.,Meyer, P.,Engen, J.R.,Georgescauld, F.; Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange.; Biochemistry, 58:1440-1449, 2019; PubMed: 30785730; DOI: 10.1021/acs.biochem.8b01308

実験手法

X-RAY DIFFRACTION (2.2 Å)