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6Q3W

Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate

Summary for 6Q3W
Entry DOI10.2210/pdb6q3w/pdb
DescriptorGalactokinase, beta-D-galactopyranose, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, ... (5 entities in total)
Functional Keywordsgalk1, fragment, fragment-bound, galactokinase 1, sugar kinase, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight170114.27
Authors
Mackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W. (deposition date: 2018-12-04, release date: 2019-01-23, Last modification date: 2024-10-16)
Primary citationMackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W.
Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.962 Å)
Structure validation

227561

数据于2024-11-20公开中

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