6Q3W
Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
Summary for 6Q3W
Entry DOI | 10.2210/pdb6q3w/pdb |
Descriptor | Galactokinase, beta-D-galactopyranose, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, ... (5 entities in total) |
Functional Keywords | galk1, fragment, fragment-bound, galactokinase 1, sugar kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 170114.27 |
Authors | Mackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W. (deposition date: 2018-12-04, release date: 2019-01-23, Last modification date: 2024-10-16) |
Primary citation | Mackinnon, S.R.,Bezerra, G.A.,Zhang, M.,Foster, W.,Krojer, T.,Brandao-Neto, J.,Douangamath, A.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Brennan, P.,Lai, K.,Yue, W.W. Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.962 Å) |
Structure validation
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