6Q03
Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine)
6Q03 の概要
エントリーDOI | 10.2210/pdb6q03/pdb |
分子名称 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, ... (4 entities in total) |
機能のキーワード | transferase, clostridium difficile, peptidoglycan, antibiotics |
由来する生物種 | Peptoclostridium difficile (strain 630) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 45867.51 |
構造登録者 | Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. (登録日: 2019-08-01, 公開日: 2019-11-27, 最終更新日: 2023-11-15) |
主引用文献 | Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine) To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.7 Å) |
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