6Q03

Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine)

6Q03 の概要

• エントリーDOI: 10.2210/pdb6q03/pdb
• 分子名称: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: transferase, clostridium difficile, peptidoglycan, antibiotics
• 由来する生物種: Peptoclostridium difficile (strain 630)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45867.51

構造登録者

Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. (登録日: 2019-08-01, 公開日: 2019-11-27, 最終更新日: 2024-11-06)

• 主引用文献: Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M.; Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine); To Be Published,

実験手法

X-RAY DIFFRACTION (1.7 Å)